Single Cell Genomics Center

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View SCGC service description and pricing

  

New capabilities:

  • Improved single cell DNA amplification with WGA-X
  • Low Coverage Sequencing (LoCoS) at <$50 per genome
  • Functional annotation included in prokaryote sequencing
  • Genomics of individual eukaryote cells and viral particles
  • Integrated analysis of genomes and optical properties of individual cells

UPCOMING CELL SORTING SESSIONS:

May 7th - 11th, 2018

June 11th - 15th, 2018

August 27th - 31st, 2018

 


Announcements & Events:

 

 llumina’s podcast on microbial single cell genomics with Ramunas Stepanauskas (also on Google Play)


 NASA Jet Propulsion Laboratory is partnering with SCGC  in spacecraft microbiome studies


 SCGC delivers soil microbiome’s "most wanted” genomes

 

   Single-cell technologies are transforming biological research

  


 

 
 
Recent SCGC-enabled discoveries:

Biology’s Dark Matter Illuminated


A collaborative study led by the U.S. Department of Energy Joint Genome Institute sheds light on metabolic features, evolutionary histories and global distribution of 28 major branches of Bacteria and Archaea that have been largely unknown to date, due to their evasion from laboratory cultivation.


Original publication: Rinke et al. 2013; Nature 499:431-437 

Nature


 A new dimension of microbial genetic diversity


Individual-based analysis reveals an incredible genetic diversity and co-variation between the core alleles and flexible gene content within wild populations of Prochlorococcus, the most abundant photosynthetic organism on Earth.

 

Original publication:  Kashtan et al. 2014; Science 344:416-420

Science

 Improved single cell genomics technology


SCGC introduces technological improvements in single cell DNA amplification, sequencing and integration with phenotype analyses.

 

Original publication:  Stepanauskas et. al. 2017; Nature Communications 8:84

Nature Communications

SCGC capabilities were established with the generous support of:

          Simons Foundation                        National Science Foundation                      Maine Technology Institute               Illumina